Product information
Product name | Anti-Collagen III Antibody （BL-22229） |
Immunogen | Recombinant fragment within Human Collagen III aa 200-400. |
Host | Rabbit |
Reactivity | Human |
Applications | Flow Cyt, ICC/IF, IP, WB |
Clonality | Polyclonal |
Isotype | IgG |
Purification | Immunogen affinity purified |
Conjugate | N/A |
Applications
WB | 1/1000. Detects a band of approximately 150 kDa (predicted molecular weight: 139 kDa). |
ICC/IF | 1/100 . |
Flow Cyt | 1/50 . |
IHC-P | N/A |
IP | 1/30 . |
Properties
Formulation | Liquid solution |
Storage buffer | Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative, 1% BSA as stablizer and 50% Glycerol. |
Storage | Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze/ thaw cycle. |
Shipped at 4°C. | Shipped at 4°C. |
Background
Type III collagen is a fibrillar forming collagen comprising three a1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. It occurs in most soft connective tissues along with type I collagen. COL3A1 gene encodes type III procollagen. Mutations in this gene are associated with type III and IV Ehlers-Danlos syndrome, and with aortic and arterial aneurysms. (PMID: 9050868; 2445760)
