| Synonyms | beta 3 tubulin,beta-4,CDCBM,CDCBM1,CFEOM3,CFEOM3A,FEOM3,M(beta)3,M(beta)6,MC1R,Neuron specific beta III Tubulin,Neuron-specific class III beta-tubulin,QccE-11995,QccE-15186,TBB3,Tubb 3,TUBB3,TUBB4,Tubulin beta 3,Tubulin beta 3 chain,Tubulin beta 4,Tubulin beta III,Tubulin beta-3 chain,Tubulin beta-4 chain,Tubulin beta-III |
| Swissprot | Q13509 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Synthesized peptide derived from the C-terminal region of mouse Tubulin β |
| Application | WB,IHC-p,IF,ELISA |
| Recommended dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
| Cellular localization | Cytoplasm>cytoskeleton. |
| Tissue specificity | Expression is primarily restricted to central and peripheral nervous system. |
| Isotype | IgG |
| Purification | Affinity purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms. |
