| Synonyms | 5' AMP activated protein kinase gamma 1 subunit,5' AMP activated protein kinase subunit gamma 1,5''-AMP-activated protein kinase subunit gamma-1,AAKG1,AMP activated protein kinase noncatalytic gamma 1 subunit,AMPK gamma 1 chain,AMPK gamma1,AMPK subunit gamma-1,AMPKg,MGC8666,PRKAG 1,PRKAG1,Protein kinase AMP activated gamma 1 non catalytic subunit,protein kinase,AMP-activated,noncatalytic gamma-1 |
| Swissprot | P54619 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human PRKAG1 |
| Application | WB,ELISA |
| Recommended dilution | WB 1:200-1:1000 |
| Concentration | 0.1 mg/mL |
| Clonality | Polyclonal |
| Cellular localization | Cytosol,Extracellular region or secreted,extracellular exosome,Nucleus,nucleoplasm,Other locations:membrane,nucleotide-activated protein kinase complex |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Western Blot analysis of Human fetal liver tissue using AMPK gamma1 Polyclonal Antibody at dilution of 1:500
