| Synonyms | ATLD2,cb16,Cyclin,DNA polymerase delta auxiliary protein,etID36690.10,fa28e03,fb36g03,HGCN8729,MGC8367,Mutagen-sensitive 209 protein,OTTHUMP00000030189,OTTHUMP00000030190,PCNA,Pcna/cyclin,PCNA,PCNAR,Polymerase delta accessory protein,Proliferating cell nuclear antigen,wu:fa28e03,wu:fb36g03 |
| Swissprot | P12004 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant human Proliferating cell nuclear antigen protein |
| Application | WB,IHC |
| Recommended dilution | WB 1:500-1:1000, IHC 1:50-1:100 |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
| Cellular localization | Nucleus |
| Tissue specificity | Highest expression level in oocyte |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. |
