| Synonyms | ATG8F,Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,LC3B,LC3II,MAP1 light chain 3 like protein 2,MAP1 light chain 3-like protein 2,MAP1A/1BLC3,MAP1A/MAP1B LC3 B,MAP1A/MAP1B light chain 3 B,MAP1ALC3,MAP1LC3B a,Map1lc3b,Microtubule associated protein 1 light chain 3 beta,Microtubule-associated protein 1 light chain 3 beta,Microtubule-associated proteins 1A/1B light chain 3B,MLP3B |
| Swissprot | Q9GZQ8 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat,Pig |
| Immunogen | A synthetic peptide of human MAP1LC3B |
| Application | WB,IHC,IF |
| Recommended dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Concentration | 1mg/ml |
| Clonality | Polyclonal |
| Cellular localization | Cytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. |
