Antibody  

XIAP Polyclonal Antibody B-IO-10000

Overview

SynonymsAP 13,API3,Apoptosis Inhibitor 3,Baculoviral IAP repeat containing 4,Baculoviral IAP Repeat Containing Protein 4,Baculoviral IAP repeat-containing protein 4,BIRC 4,BIRC4,E3 ubiquitin-protein ligase XIAP,hIAP-3,hIAP3,HILP,IAP 3,IAP like protein,IAP-3,IAP-like protein,IAP3,ILP 1,ILP,ILP1,Inhibitor of apoptosis protein 3,Inhibitor of Apoptosis X Linked,Mammalian IAP Homologue A,MIHA,X linked IAP,X linked inhibitor of apoptosis,X linked inhibitor of apoptosis E3 ubiquitin protein ligase,X linked inhibitor of apoptosis protein,X-linked IAP,X-linked inhibitor of apoptosis protein,Xiap,XIAP,XLP2
SwissprotP98170
SourceRabbit
ReactivityHuman,Mouse,Rat
ImmunogenSynthetic peptide of human XIAP
ApplicationWB,ELISA
Recommended dilutionWB 1:200-1000, ELISA 1:1000-2000
Concentration0.6mg/mL
ClonalityPolyclonal

Properties

Cellular localizationCytoplasm.
Tissue specificityUbiquitous, except peripheral blood leukocytes.
IsotypeIgG
PurificationAffinity purification
ConjugationUnconjugated
Storage instructionsStore at -20℃. Avoid freeze / thaw cycles.
Storage bufferPBS with 0.05% sodium azide, 50% glycerol, PH7.3
BackgroundThis gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. 

Images

B-IO-10000-WB.png

Western Blot analysis of Human normal kidney 

tissue using XIAP Polyclonal Antibody at dilution of 1/400